Difference between revisions of "Homologous recombination"

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Latest revision as of 17:26, 26 February 2021

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Genetic recombination in which nucleotide sequences are exchanged between two similar or identical molecules of DNA. Cells use HR to repair DNA double strand breaks induced in S and G2 phase of the cell cycle by copying the intact counterpart of the sister DNA strand. HR is potentially error-free.

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from ICRP Publication 131, 2015

HR takes place in S and G2 phase cells to repair a damaged region of DNA by copying the intact counterpart of the sister DNA strand. HR is potentially error-free.