Difference between revisions of "Linear-quadratic dose response model"
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A statistical model that expresses the risk of an effect E (e.g. disease, death, or abnormality) as the sum of two components: one proportional to dose (linear term) and the other proportional to the square of dose (quadratic term). | A statistical model that expresses the risk of an effect E (e.g. disease, death, or abnormality) as the sum of two components: one proportional to dose (linear term) and the other proportional to the square of dose (quadratic term). | ||
| − | E=αD+βD<sup>2</sup>, where D is dose. For cell survival: S =exp-(αD+βD<sup>2</sup>). | + | ''E=αD+βD<sup>2</sup>'', where D is dose. For cell survival: ''S =exp-(αD+βD<sup>2</sup>)''. |
=== from [[ICRP Publication 103]], 2007 & from [[ICRP Publication 118]], 2012 === | === from [[ICRP Publication 103]], 2007 & from [[ICRP Publication 118]], 2012 === | ||
A statistical model that expresses the risk of an effect (e.g., disease, death, or abnormality) as the sum of two components, one proportional to dose (linear term) and the other one proportional to the square of dose (quadratic term). | A statistical model that expresses the risk of an effect (e.g., disease, death, or abnormality) as the sum of two components, one proportional to dose (linear term) and the other one proportional to the square of dose (quadratic term). | ||
Latest revision as of 17:48, 26 February 2021
A statistical model that expresses the frequency of an effect (e.g., disease, death, or abnormality) as the sum of two components, one proportional to dose (linear term) and the other one proportional to the square of dose (quadratic term).
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Previous glossary entries
from ICRP Publication 131, 2015
A statistical model that expresses the risk of an effect E (e.g. disease, death, or abnormality) as the sum of two components: one proportional to dose (linear term) and the other proportional to the square of dose (quadratic term).
E=αD+βD2, where D is dose. For cell survival: S =exp-(αD+βD2).
from ICRP Publication 103, 2007 & from ICRP Publication 118, 2012
A statistical model that expresses the risk of an effect (e.g., disease, death, or abnormality) as the sum of two components, one proportional to dose (linear term) and the other one proportional to the square of dose (quadratic term).
