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[[File:Glossary Icon-2.png|100px|frameless|right|link=ICRP Glossary]]
A spectrum of responses involving deterministic haematopoietic, gastrointestinal, cardiovascular, and central nervous system reactions to a large radiation dose received acutely or subacutely to all or most of the body. It follows a dose-dependent clinical course divided into prodromal, latent, and manifest periods of illness.(from [[ICRP Publication 118]], 2012)
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