Homologous recombination
Jump to navigation
Jump to search
Genetic recombination in which nucleotide sequences are exchanged between two similar or identical molecules of DNA. Cells use HR to repair DNA double strand breaks induced in S and G2 phase of the cell cycle by copying the intact counterpart of the sister DNA strand. HR is potentially error-free.
Return to Glossary
Previous glossary entries
from ICRP Publication 131, 2015
HR takes place in S and G2 phase cells to repair a damaged region of DNA by copying the intact counterpart of the sister DNA strand. HR is potentially error-free.
