Difference between revisions of "Non-homologous end joining"

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Latest revision as of 19:30, 26 February 2021

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An error-prone DNA double strand break repair pathway that is exclusively activated in the G1 cell cycle phase and to a varying extent in S and G2 phases of the cell cycle.

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from ICRP Publication 131, 2015

NHEJ repair takes place in non-cycling cells and variously in all cycle phases, and is dependent on the repair proteins Ku70, Ku80, and DNA-dependent protein kinase catalytic subunit (DNA-PKcs).