Non-homologous end joining
Jump to navigation
Jump to search
An error-prone DNA double strand break repair pathway that is exclusively activated in the G1 cell cycle phase and to a varying extent in S and G2 phases of the cell cycle.
Return to Glossary
Previous glossary entries
from ICRP Publication 131, 2015
NHEJ repair takes place in non-cycling cells and variously in all cycle phases, and is dependent on the repair proteins Ku70, Ku80, and DNA-dependent protein kinase catalytic subunit (DNA-PKcs).
